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-as of [29 JUNE 2024]–
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“dex tro meth OR fan”
(5 syllables)
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“dextromethorphan hydrobromide salt”
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*DXM / DM*
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-[dextro-methorphan] is a [drug] of the [morphinan class] with [βsedative’ / ‘dissociative’ / ‘stimulant’] properties (at higher doses)-
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[it is a ‘cough suppressant’ in many over-the-counter cold and cough medicines including ‘generic labels’ + ‘store brands’…]
‘benylin DM’
‘mucinex DM’
‘camydex-20 tablets’
‘robitussin’
‘NyQuil’
‘dimetapp’
‘vicks’
‘coricidin’
‘delsym’
‘TheraFlu’
‘cheracol D’
(…and others…)
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(‘dextromethorphan’ has also found numerous other uses in ‘medicine’, ranging from…)
‘pain relief’
(as either the ‘primary analgesic’ or an ‘opioid potentiator’)
TO
(‘psychological applications’ in treatment of ‘addiction’)
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(it is sold in a variety of ‘forms’…)
‘syrup’
‘tablet’
‘spray’
‘lozenge’
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(in its pure form, ‘dextromethorphan’ occurs as a ‘white powder’)
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(DXM is also used recreationally)
(when exceeding label-specified maximum dosages, ‘dextromethorphan’ acts as a ‘dissociative anesthetic’)
(its ‘mechanism of action’ is via multiple effects, including actions as a ‘non-selective serotonin re-uptake inhibitor’ + a ‘sigma-1 receptor agonist’)
(DXM – and its major metabolite ‘dextrorphan’ – also act as an ‘NMDA receptor antagonist’ at high doses, which produces effects similar to (yet distinct from) the ‘dissociative states’ created by other dissociative anesthetics such as ‘ketamine’ + ‘phencyclidine’)
(further, the metabolite 3-methoxymorphinan also metabolizes into 3-hydroxymorphinan which has the potent ‘neuro-protective’ + ‘neuro-trophic’ effects of dextrorphan (thus a 2nd-level metabolite of DXM) produces ‘local anesthetic effects’ in ‘rats’ with potency above ‘dextrorphan’, but below that of DXM)
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