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-as of [9 APRIL 2024]–
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(“eye color” is a ‘polygenic phenotypic character’ determined by 2 distinct factors…)
*the ‘pigmentation’ of the eye’s ‘iris’*
*the ‘frequency-dependence’ of the scattering of light by the turbid medium in the stroma of the ‘iris’*
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(in ‘humans’, the ‘pigmentation’ of the ‘iris’ varies from ‘light brown’ to ‘black’,
depending on the concentration of ‘melanin’ in the
iris pigment epithelium
(located on the back of the iris),
the melanin content within the iris stroma
(located at the front of the iris),
and the cellular density of the ‘stroma’)
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(the appearance of blue and green, as well as hazel eyes, results from the ‘tyndall scattering’ of light in the stroma, a phenomenon similar to that which accounts for the blueness of the sky called ‘rayleigh scattering’)
(neither blue nor green pigments are ever present in the human iris or ‘ocular fluid’)
(‘eye color’ is thus an instance of structural color and varies depending on the lighting conditions, especially for ‘lighter-colored eyes’)
(the ‘brightly colored eyes’ of many bird species result from the presence of other pigments, such as pteridines, purines, and ‘carotenoids’)
(‘humans’ and other ‘animals’ have many ‘phenotypic variations’ in ‘eye color’)
(the ‘genetics’ of eye color are complicated, and color is determined by multiple ‘genes’)
(so far, as many as 15 genes have been associated with ‘eye color inheritance’)
(some of the eye-color genes include ‘OCA2′ + ‘HERC2′)
(the earlier belief that blue eye color is a simple recessive trait has been shown to be incorrect)
(the ‘genetics’ of eye color are so complex that almost any parent-child combination of ‘eye colors’ can occur)
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(however, ‘OCA2 gene polymorphism’, close to proximal 5β² regulatory region, explains most ‘human eye-color variation’)
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