*serotonin*

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C10H12N2O

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(/ˌsɛrəˈtoʊnɪn/)

(or sɪərə-/)
(?)

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*AKA* —>

5-hydroxytryptamine
(5-HT)

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*’mono-amine neuro-transmitter’*

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(bio-chemically derived from ‘tryptophan’, ‘serotonin’ is primarily found in

the ‘gastro-intestinal (GI) tract (GI tract),

blood platelets,

and the central nervous system (CNS) of animals,

(*including humans*)

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(it is popularly thought to be a contributor to feelings of ‘well-being’ + ‘happiness’)

(approximately 90% of the human body’s total serotonin is located in the ‘entero-chromaffin cells’ in the ‘GI tract’, where it is used to regulate ‘intestinal movements’)

(the ‘serotonin’ is secreted ‘luminally’ + ‘baso-laterally’ which leads to increased ‘serotonin uptake’ by circulating ‘platelets’ + ‘activation’ after ‘stimulation’, which gives increased stimulation of ‘myenteric neurons’ + ‘gastro-intestinal motility’)

(the remainder is synthesized in ‘serotonergic neurons’ of the ‘CNS’, where it has various functions)

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(these include the regulation of…)

‘mood’

‘appetite’

‘sleep’

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(‘serotonin’ also has some ‘cognitive functions’)
(including ‘memory’ + ‘learning’)

(‘modulation’ of ‘serotonin’ at ‘synapses’ is thought to be a ‘major action’ of several classes of ‘pharmacological anti-depressants’)

(‘serotonin’ secreted from the ‘entero-chromaffin cells’ eventually finds its way out of ‘tissues’ into the ‘blood’)

(there, it is actively taken up by ‘blood platelets’, which store it)

(when the ‘platelets’ bind to a ‘clot’, they release ‘serotonin’, where it serves as a ‘vaso-constrictor’ and helps to regulate ‘hemo-stasis’ + ‘blood clotting’)

(‘serotonin’ is also a ‘growth factor’ for some types of ‘cells’, which may give it a role in ‘wound healing’)

(there are various ‘serotonin receptors’)

(‘serotonin’ is metabolized mainly to ‘5-HIAA’, chiefly by the ‘liver’)

(‘metabolism’ involves first ‘oxidation’ by ‘mono-amine oxidase’ to the corresponding ‘aldehyde’)

(this is followed by ‘oxidation’ by ‘aldehyde dehydrogenase’ to ‘5-HIAA’, the ‘indole acetic acid derivative’)

(the latter is then excreted by the ‘kidneys’)

(in addition to ‘animals’, ‘serotonin’ is found in ‘fungi’ + ‘plants’)

(serotonin’s presence in ‘insect venoms’ + ‘plant spines’ serves to cause ‘pain’, which is a side-effect of ‘serotonin injection’)

(‘serotonin’ is produced by ‘pathogenic amoebae’, and its effect on the ‘gut’ causes ‘diarrhea’)

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(its ‘widespread presence’ in many ‘seeds’ + ‘fruits’ may serve to ‘stimulate’ the ‘digestive tract’ into expelling the ‘seeds’)

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*WIKI-LINK*

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👈👈👈☜*“NEURO-TRANSMITTERS”* ☞ 👉👉👉

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💕💝💖💓🖤💙🖤💙🖤💙🖤❤️💚💛🧡❣️💞💔💘❣️🧡💛💚❤️🖤💜🖤💙🖤💙🖤💗💖💝💘

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*🌈✨ *TABLE OF CONTENTS* ✨🌷*

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🔥🔥🔥🔥🔥🔥*we won the war* 🔥🔥🔥🔥🔥🔥