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There are yet unsolved problems in neuroscience, although some of these problems have evidence supporting a hypothesized solution, and the field is rapidly evolving.
These problems include…
Sensation, perception and movement
Perception:
How does the brain transfer sensory information into coherent, private percepts?
What are the rules by which perception is organized?
What are the features/objects that constitute our perceptual experience of internal and external events?
How are the senses integrated?
What is the relationship between subjective experience and the physical world?
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Movement
How can we move so controllably, even though the motor nerve impulses seem haphazard and unpredictable?
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Learning and memory
Learning and memory:
Where do our memories get stored and how are they retrieved again?
How can learning be improved?
What is the difference between explicit and implicit memories?
What molecule is responsible for synaptic tagging?
Neuroplasticity:
How plastic is the mature brain?
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Cognition and decisions
How and where does the brain evaluate reward value and effort (cost) to modulate behavior?
How does previous experience alter perception and behavior?
What are the genetic and environmental contributions to brain function?
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Language
Language:
How is it implemented neurally?
What is the basis of semantic meaning?
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Mind-body connection
Development and evolution:
How and why did the brain evolve?
What are the molecular determinants of individual brain development?
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Free will, particularly the neuroscience of free will
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Diseases:
What are the neural bases (causes) of mental diseases like
psychotic disorders
(e.g. mania, schizophrenia),
Amyotrophic lateral sclerosis,
Parkinson’s disease,
Alzheimer’s disease,
or addiction?
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Is it possible to recover loss of sensory or motor function?
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Sleep
What is the biological function of sleep?
Why do we dream?
What are the underlying brain mechanisms?
What is its relation to anesthesia?
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Computational neuroscience
Computational theory of mind:
What are the limits of understanding thinking as a form of computing?
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Computational neuroscience
How important is the precise timing of action potentials for information processing in the neocortex?
Is there a canonical computation performed by cortical columns?
How is information in the brain processed by the collective dynamics of large neuronal circuits?
What level of simplification is suitable for a description of information processing in the brain?
What is the neural code?
How do general anesthetics work?
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Neural computation
What are all the different types of neuron and what do they do in the human brain?
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“noogenesis”
the emergence and evolution of intelligence:
What are the laws and mechanisms – of new idea emergence
(insight, creativity synthesis, intuition, decision-making, eureka);
development (evolution) of an individual mind in the ontogenesis, etc.?
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References
^ Sejnowski, Terrence J.; Hemmen, J. L. van (2006). 23 problems in systems neuroscience (PDF). Oxford [Oxfordshire]: Oxford University Press. ISBN 978-0-19-514822-0.
^ Tononi, Giulio; Koch, Christof (2015). “Consciousness: Here, there and everywhere?”. Philosophical Transactions of the Royal Society B: Biological Sciences. 370 (1668): 20140167. doi:10.1098/rstb.2014.0167. PMC 4387509. PMID 25823865.
^ University of Copenhagen (24 January 2007). “Thinking With The Spinal Cord?”. ScienceDaily. Retrieved 25 May 2016.
^ “A Database Of All Things Brainy”
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External links
The Human Brain Project Homepage
David Eagleman (August 2007). “10 Unsolved Mysteries of the Brain”. Discover Magazine.
Dennett D (April 2001). “Are we explaining consciousness yet?”.
Cognition. 79 (1–2): 221–37. doi:10.1016/S0010-0277(00)00130-X. PMID 11164029.
en.wikipedia.org /wiki/List_of_unsolved_problems_in_neuroscience
List of unsolved problems in neuroscience
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