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*”non-steroidal anti-inflammatory drug”*
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-as of [28 APRIL 2024]–
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*TYPES* –>
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(NSAIDs are a ‘drug class’ that groups together drugs that provide…)
‘analgesic effects’
(aka ‘pain-killing’)
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‘anti-pyretic effects’
(aka ‘fever-reducing’)
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‘anti-inflammatory effects’
(in higher doses)
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-the term non-steroidal distinguishes these drugs from ‘steroids’, which (among a broad range of other effects) have a similar eico-sanoid-depressing, anti-inflammatory action–
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(first used in ‘1960’, the term served to distance new drugs from ‘steroid-related iatro-genic tragedies’)
(‘latro-genic tragedies’ are negative health effects caused by treatment of an ‘underlying disease’)
(the most prominent members of this group of drugs, aspirin / ibuprofen ‘naproxen’, are all available over the counter in most countries)
(“paracetamol” (acetaminophen) is generally not considered an NSAID because it has only little anti-inflammatory activity)
(it treats pain mainly by blocking COX-2 mostly in the central nervous system, but not much in the rest of the body)
(most NSAIDs inhibit the activity of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), and thereby the synthesis of prostaglandins and thromboxanes)
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(it is thought that inhibiting ‘COX-2’ leads to the [‘anti-inflammatory’ / ‘analgesic’ / ‘anti-pyretic’] effects and that those ‘NSAIDs’ also inhibiting ‘COX-1’ (particularly aspirin) may cause ‘gastro-intestinal bleeding’ + ‘ulcers’)
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*👨🔬🕵️♀️🙇♀️*SKETCHES*🙇♂️👩🔬🕵️♂️*
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💕💝💖💓🖤💙🖤💙🖤💙🖤❤️💚💛🧡❣️💞💔💘❣️🧡💛💚❤️🖤💜🖤💙🖤💙🖤💗💖💝💘
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*🌈✨ *TABLE OF CONTENTS* ✨🌷*
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🔥🔥🔥🔥🔥🔥*we won the war* 🔥🔥🔥🔥🔥🔥